26MakinAJ, WendonJ, WilliamsR
Your maintenance dose might be lower than your peak dose, but completely discontinuing medication removes the metabolic support keeping your appetite normalized and your weight stable
It helps suppress appetite, increases satiety, slows the emptying of your stomach, and helps regulate insulin. In other words, GLP-1 helps: Reduce hunger Increase feelings of fullness Improve blood sugar control Slow digestion so you stay satisfied longer But todays modern lifestyle, which often includes high stress levels, lack of quality sleep, and processed foods, can interfere with your bodys ability to naturally regulate these hunger signals
Sertraline is also a weak to moderate inhibitor of CYP2D6, which can affect the metabolism of other drugs using this pathway
Conversely, in chronic alcohol use, ethanol is an inducer of CYP2E1, leading to a potential increase in the formation of NAPQI should an overdose of acetaminophen occur